Virtual-Integrated Twin for Autonomous Lifesaving (VITAL)
Dept of Defense · DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
This notice is not accepting responses (deadline was Jun 24, 2026, 8:00 PM EDT).
Page kept for research and related open opportunities below. For current work in this category, use the related notices or browse hubs.
- Response deadline
- Jun 24, 2026, 8:00 PM EDT
- Posted
- Apr 8, 2026
- Solicitation
- DARPA-PS-26-26
- Set-aside
- None listed
- Place of performance
- —
- Contracting office
- DEF ADVANCED RESEARCH PROJECTS AGCY · ARLINGTON · VA
- Source
- SAM.gov · updated May 9, 2026
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative approaches to address challenges in developing continuously updating digital twin models of the cardiovascular system that combine patient data with biological physics to simulate in real time possible interventions and to predict their outcomes before actual intervention on a patient. The VITAL program will establish a foundation for causal, prediction-driven decision support in medicine, enabling clinicians and future autonomous systems to evaluate treatment options before they are applied. By defining when mechanistic digital twins, reduced-order models, and data-driven inference are reliable and actionable, VITAL will shift medical care from reactive assessment to anticipatory intervention. This capability has the potential to improve outcomes across acute, chronic, and emergent clinical settings.
What similar awards have paid
Real federal awards already on the books in a similar lane — so you can size the opportunity, not guess. This is public history, not a bid price, cost estimate, or prediction that you will win.
Typical award size
$404,976
Middle of the pack for similar past awards
Most similar awards fall between $45,429 and $2.81M
Who has won work like this
Public awardees in this lane — useful for competitor scan or teaming ideas, not a ranked list of “best” firms.
- 1ADVANCED TECHNOLOGY INTERNATIONAL5 awards$2.27B
- 2AMGEN USA INC2 awards$714.70M
- 3SIGA TECHNOLOGIES, INC.1 award$624.44M
- 4ICON GOVERNMENT AND PUBLIC HEALTH SOLUTIONS, INC.5 awards$383.82M
- 5ALLUCENT GOVERNMENT SERVICES (US) LLC5 awards$375.68M
- 6TECHNICAL RESOURCES INTERNATIONAL, INC.9 awards$363.64M
- 7MAPP BIOPHARMACEUTICAL, INC.4 awards$315.08M
- 8ALBERT B. SABIN VACCINE INSTITUTE, INC. (THE)2 awards$305.87M
Drawn from official USAspending contract records in our index. Always confirm requirements on the SAM.gov notice before you bid.
Intelligence only — not legal advice or a guarantee of award. Always verify requirements on the official SAM.gov notice. Past award amounts are public history, not a suggested bid or prediction. Notice ID 5c6a433f8f6c4965a787ef4a01191d72.