GUARDIAN
Dept of Defense · DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
This notice is not accepting responses (deadline was Apr 7, 2026, 4:00 PM EDT).
Page kept for research and related open opportunities below. For current work in this category, use the related notices or browse hubs.
- Response deadline
- Apr 7, 2026, 4:00 PM EDT
- Posted
- Feb 18, 2026
- Solicitation
- DARPA-PS-26-17
- Set-aside
- None listed
- Place of performance
- —
- Contracting office
- DEF ADVANCED RESEARCH PROJECTS AGCY · ARLINGTON · VA
- Source
- SAM.gov · updated Jul 5, 2026
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative approaches to controllably eliminate invasive species from defined areas, primarily focused on New World Screwworm (NWS) and Brown Tree Snake (BTS)(Guam), using genetic drive technologies (GDT). GUARDIAN is composed of three optionsTechnical Areas (TAs). The first Option TA is focused on BTS eradication. Performerroposers are expected to complete modeling and laboratory testing of genetic elements in the 18-month Phase 1 and contained (laboratory or greenhouse) testing during the 18-month Phase 2. Option TA1 will emphasize: genetic precision to ensure off-target effects and GDT resistance is minimized; GDT control by designing counter measures/GDT immunization to add additional safeguards; and fieldability by ensuring laboratory and contained testing meets regulatory agency requirements to proceed to field trials and that the GDT meets requirements needed for impactful population reduction goals. Option TA2 seeks to develop innovative cell cultures methods that accelerate the study of gene drives in eukaryotic organisms and should contain elements that support Option TA1. The third Option TA focuses on population modeling of gene drives, particularly that of NWS and BTS.
What similar awards have paid
Real federal awards already on the books in a similar lane — so you can size the opportunity, not guess. This is public history, not a bid price, cost estimate, or prediction that you will win.
Typical award size
$404,976
Middle of the pack for similar past awards
Most similar awards fall between $45,429 and $2.81M
Who has won work like this
Public awardees in this lane — useful for competitor scan or teaming ideas, not a ranked list of “best” firms.
- 1ADVANCED TECHNOLOGY INTERNATIONAL5 awards$2.27B
- 2AMGEN USA INC2 awards$714.70M
- 3SIGA TECHNOLOGIES, INC.1 award$624.44M
- 4ICON GOVERNMENT AND PUBLIC HEALTH SOLUTIONS, INC.5 awards$383.82M
- 5ALLUCENT GOVERNMENT SERVICES (US) LLC5 awards$375.68M
- 6TECHNICAL RESOURCES INTERNATIONAL, INC.9 awards$363.64M
- 7MAPP BIOPHARMACEUTICAL, INC.4 awards$315.08M
- 8ALBERT B. SABIN VACCINE INSTITUTE, INC. (THE)2 awards$305.87M
Drawn from official USAspending contract records in our index. Always confirm requirements on the SAM.gov notice before you bid.
Intelligence only — not legal advice or a guarantee of award. Always verify requirements on the official SAM.gov notice. Past award amounts are public history, not a suggested bid or prediction. Notice ID aa1e055e84e74d8b97d67753d5bb8347.